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Ontology/Semantics Specialist

Axle

Rockville, MD permanent

Posted: February 24, 2026

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Quick Summary

We're looking for an Ontology/Semantics Specialist to join our team, working on projects with top research organizations and facilities across the country, including the National Institutes of Health, to develop and apply research tools and techniques to empower decision-making and accelerate research discoveries.

Job Description

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

• 100% Medical, Dental & Vision Coverage for Employees

• Paid Time Off and Paid Holidays

• 401K match up to 5%

• Educational Benefits for Career Growth

• Employee Referral Bonus

• Flexible Spending Accounts:

• Healthcare (FSA)

• Parking Reimbursement Account (PRK)

• Dependent Care Assistant Program (DCAP)

• Transportation Reimbursement Account (TRN)

Position Overview

Axle is seeking an Ontology/Semantics Specialist that will support NIH’s enterprise semantic infrastructure by managing vocabulary services, metadata frameworks, and ontology development. This role ensures data standardization, interoperability, and integration across biomedical research systems.

This opportunity supports a blended team providing PMO leadership, IT engineering and sustainment, biomedical informatics and data science, as well as policy, process, communications, and training functions. The work enables both NIH basic research and the NIH clinical research enterprise. 

Key Responsibilities

• Tracks semantics of research data, develops graphical user interfaces to HPC resources, recommending, utilizing, and configuring HPC workflow management tools.

• Provides training, tutorials, communication, and education on HPC resources to stakeholders and teams. Leads HPC projects.

• Experience working in Enterprise Vocabulary Services.

• Develop and maintain biomedical ontologies and metadata standards.

• Support Common Data Elements (CDE) management within caDSR.

• Collaborate with stakeholders to ensure semantic harmonization across systems.

• Develop APIs and services supporting semantic integration.

• Document semantic models and contribute to governance processes.

Qualifications

• Bachelor’s degree plus four (4) years of experience.

• Experience in biomedical ontology development or semantic technologies.

• Knowledge of metadata standards and controlled vocabularies.

• Familiarity with API development and data integration frameworks.

• Experience with NIH/NIH systems preferred.

Disclaimer:

The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [email protected]

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range

$115,000 - $135,000 USD

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