Medical Evidence Lead- Lung Cancer

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, daring thinking, and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe. Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to build a strong culture of collaboration and partnership by engaging face-to-face in our offices 3 days a week. Our head office and BlueSky Hub in downtown Toronto are purposely crafted with collaboration in mind, providing space where teams can come together to strategize, brainstorm, and connect on key projects. Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca is an excellent place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking bold actions to address some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention. The Medical Evidence Lead will be accountable for driving the evidence generation strategy and execution for lung cancer or other assigned tumor areas , including both pre-launch and post-launch products, with a strong focus on generating meaningful, translatable evidence that supports AstraZeneca Canada’s business priorities. The successful candidate will be at the forefront of strengthening data partnerships, advancing emerging evidence generation technologies and methodologies, and leading the measurement of health care transformation and implementation science initiatives. As a senior leader within the medical evidence team, this role may have people leadership and mentoring responsibilities. Responsibilities: Plan and deliver observational research and R eal W orld E vidence (RWE) studies in lung cancer or assigned t umor area s Lead the development and execution of comprehensive evidence plans for both pre-launch and launched products to address full breadth of internal and external partner needs Identify , establish , and strengthen data partnerships with healthcare providers, academic organizations, data vendors, and health systems to enhance the breadth and depth of evidence generation opportunities across the AZ portfolio . Advance the application of emerging technologies and novel methodologies in evidence generation, including innovative data sources, digital technology, and AI-driven analytics, to improve the impact and efficiency of research projects. Interpret study fin dings, develop performance measures and KPIs to assess study or implementation program effectiveness, and s upport the translation of evidence into clinical practice and measuring impact on patient and health system outcomes. Drive use of advanced biostatistics and sophisticated data analytics throughout all stages of research, ensuring rigorous study design and robust interpretation of data using varied healthcare databases. Collaborate with key external experts, including academic-clinical investigators, health outcomes researchers, and contract research organizations (CROs). Liaise with global counterparts for all evidence generating activities and lead the review and approval process for local studies at AstraZeneca Canada Ensure the timely achievement of project-specific breakthroughs and dissemination of scientific publications (e.g., conference presentations, peer-reviewed journal manuscripts) Develop and lead communication and knowledge translation plan for all evidence generating activities and ensure presentation of study results to appropriate internal and external partners (e.g., HTA meetings) Be responsible for site start-up activities such as ethics submission, informed consent review, development and finalization of research study agreements and follow-up and maintenance of all study related activities, if required , in accordance with AstraZeneca and international regulatory requirements . Develop and maintain study budget, timelines and resources and ensure appropriate update s are made to internal tracking systems Complete feasibility assessments for Global Non-Interventional Studies and provide in-house epidemiology, statistics, and observational research methodology expertise to cross-functional partners. Prepare, review, and maintain study documents in accordance with external guidelines and AstraZeneca SOPs. Qualifications: Master’s degree or PhD in epidemiology, health services/systems , biostatistics, or a related discipline. Experience leading RWE studies in Oncology (multiple tumor areas) is required Experience in identifying and building collaborative data partnerships with academic institutions, health systems, data custodians , or technology companies to expand research capabilities. Proven track record to advance and apply emerging technologies (such as digital platforms, real-world data, and AI analytics) and novel methodologies to observational and interventional research. In-depth understanding and hands-on experience in biostatistics and advanced data analytics, including proficiency with large healthcare databases and statistical programming tools. Strong track record in generating, synthesizing, and communicating significant and actionable evidence that supports clinical, regulatory, and business decision-making. Excellent knowledge of observational study methodology (design and interpretation) and externally sponsored research (including clinical and pre-clinical research). Excellent interpersonal, verbal, and written communication skills; proven track record to interact successfully with a wide range of internal and external stakeholders, including governments, payers, academic researchers, and physicians. Demonstrated leadership ability in a team environment and strong project management skills. Self-motivated—able to move actions forward, make informed decisions, and deliver with limited supervision. Effective time management skills. Good knowledge of MS Office (Word, Excel, PowerPoint). Knowledge of French is an asset. Medical Evidence Lead: > 3 years proven experience directly leading RWE studies in Oncology and demonstrated cross-functional leadership . A nnual base salary for this position ranges from $135,362 to $177,663. AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances. In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program. Great People want to Work with us! Find out why: GTAA Top Employer Award for 10 years Top 100 Employers Award Canada’s Most Admired Corporate Culture Learn more about working with us in Canada View our YouTube channel This is the place to make a meaningful impact – on patients’ lives and your personal growth. It’s both exciting and inspiring, and it’s what keeps us motivated every day. Ready to make a difference? Apply now! AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com ( mailto:AZCHumanResources@astrazeneca.com ). AI Disclosure : We are using AI as part of the recruitment process Vacancy: This advertisement relates to a current vacancy. Date Posted 02-Jan-2026 Closing Date 22-Jan-2026 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.