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Manager, R&D Laboratory Operations

Natera

San Carlos, CA (Natera - SF Bay Area) permanent

Posted: January 30, 2026

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Quick Summary

We are seeking a highly analytical, strategic and implemental Laboratory Operations Manager to lead an R&D lab support team. The Laboratory Operations Manager will support the R&D department by creating, maintaining and managing high functioning laboratories. This role focuses on optimizing operations and management in the areas of EHS, inventory, procurement, equipment and space.

Job Description

POSITION SUMMARY:

We are seeking a highly analytical, strategic and implemental Laboratory Operations Manager to lead an R&D lab support team. The Laboratory Operations Manager will support the R&D department by creating, maintaining and managing high functioning laboratories. This role focuses on optimizing operations and management in the areas of EHS, inventory, procurement, equipment and space. The ideal candidate will drive lab support efficiency, continuous improvement, and align lab support strategies with business needs.

PRIMARY RESPONSIBILITIES:

• Work closely with all R&D teams and counterparts in the R&D Operations team to ensure the necessary environment, facilities, reagents & supplies, materials, and equipment for performing R&D projects

• Work primarily with the R&D Laboratory Operations team and outside vendors to plan and perform duties in the areas of EHS, inventory, procurement, equipment and space

• Plan, oversee and execute day-to-day R&D lab operations, including but not limited to lab safety and compliance, adequate lab supplies and inventory, sample procurement, and equipment usage

• Plan and forecast consumption levels of reagents/consumables based on current and upcoming project load to prevent redundant ordering and limit waste/scrap

• Provide updates and logistical oversight on sample procurement

• Compile, analyze and forecast spending

• Develop and implement tools for efficient use of high capital expense equipment

• Analyze and report on KPIs

• Perform lab walkthroughs to identify, control and mitigate operational risks

• Assess, make suggestions, and optimize laboratory workflow and logistics to improve department and laboratory efficiency and productivity

• Identify, propose and implement changes/modifications to documentation systems and procedures to ensure compliance

• Ensure that R&D labs are following relevant GxPs and CLIA practices

• Write, review and implement SOPs

• Hire and provide onboard training

• Conduct hands-on lab support activities

• Drive continuous improvement initiatives to enhance performance and efficiency of lab operations

QUALIFICATIONS:

• BS or BA in science, engineering, business or related field

• Seven plus years of combined experience in areas of lab operations, scientific research, EHS QA/QC, facilities and/or general management

• Minimum of five years of previous laboratory management experience

• Minimum of three years of people management experience

KNOWLEDGE, SKILLS, AND ABILITIES:

• Excellent analytical skills

• Strong capability in planning and execution

• Excellent written and oral communication skills

• Excellent organizational and leadership skills

• Strong ability to multitask, prioritize and deliver in a fast paced and dynamic work environment

• Ability to think creatively and analytically with exceptional level of organization, time management, problem solving, and reliability

• Great attention to details

• Great ability to optimize workflows by identifying and eliminate redundancies

• Proactive and self-motivated

• Extensive experience in R&D lab support

• Working knowledge of EHS and OSHA regulations and policies

• Working knowledge of GxP's

• Proficient in basic molecular biology techniques

• Experience operating NGS platforms and Liquid Handlers

• Team player

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:


Annual performance incentive bonus


Long-term equity awards


Comprehensive health benefits (medical, dental, vision)


401(k) with company match


Generous paid time off and company holidays


Additional wellness and work-life benefits

Compensation Range
$124,600—$155,800 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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