Manager, Internal Audit

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

The Manager of Internal Audit will play a pivotal role in building, executing and enhancing the company’s newly revamped internal audit function, with a strong emphasis on Sarbanes-Oxley (SOX) compliance and operational audits. This individual will contribute to building a scalable and effective audit program, supporting risk management, control evaluation, and governance processes. The role requires someone who can manage co-sourced resources, collaborate across departments, and deliver value-added insights to improve business processes and controls. Reporting to the Head of Internal Audit, this role will work closely with finance, operational, and other members of management to maintain transparency, integrity, and accountability within the organization.

This position will be hybrid in office two days per week in Stamford, CT and may require occasion travel (~20%).

Job Responsibilities

• Lead and manage assigned areas of the SOX program, including risk assessment, scoping, testing, and reporting.

• Perform walkthroughs and document business processes, risks, control activities, and supporting technologies.

• Review workpapers and assess the design and operating effectiveness of internal controls.

• Draft and deliver audit results, ensuring timely and actionable feedback to stakeholders.

• Serve as a subject matter expert on SOX, risk, and control, advising business and risk partners.

• Ability to formulate opinions and communicate perspectives to stakeholders in a timely manner.

• Conduct audits and ad-hoc internal audit projects aligned with the annual audit plan.

• Manage multiple workstreams at the same time and prioritize tasks for team members.

• Provide training and guidance to internal audit staff and control owners on SOX requirements and best practices.

• Identify opportunities for process improvement and control enhancement.

• Collaborate with external auditors, co-sourced partners, and internal stakeholders.

• Support the growth of the internal audit function, including recruiting and onboarding efforts.

• Contribute to the evolution of audit practices by incorporating emerging technologies and process refinements.

• Participate in company-wide risk assessments and integrate findings into audit planning.

• Maintain awareness of regulatory changes and industry best practices.

Education, Experience, and Skills

• Bachelor’s degree in Accounting, Finance, Economics, IT or other related field; advanced degree a plus.

• Certified Internal Auditor (CIA) or Certified Public Accountant (CPA) required.

• 7+ years of experience in auditing and/or compliance, including SOX program management.

• Experience managing co-sourced resources and leading audit teams.

• Strong understanding of internal control frameworks, financial reporting, enterprise risk frameworks.

• Familiarity with enterprise resource planning (ERP) systems, GRC platforms, and audit management software. Experience with NetSuite or Audit Board a plus.

• Experience within the Healthcare industry.

• Excellent project management, analytical, and communication skills.

• Ability to build relationships across all levels of the organization.

• High attention to detail and commitment to accuracy and transparency.

• Ability to work in a fast paced, action-oriented environment.

Work Environment

This is a hybrid position requiring both in-office and remote work. The employee will work from our office location in Stamford, CT and remotely from a home office or other suitable location with reliable high-speed internet access. In-office work is performed in a professional office setting with standard lighting, temperature control, and low to moderate noise levels. Remote work is performed in a climate-controlled environment. Standard office equipment including computer, phone, and video conferencing tools are used in both settings. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs.

Physical Demands

This is a sedentary role with physical demands including:

• Sitting for extended periods (up to 8 hours per day).

• Repetitive use of hands and fingers for typing and mouse operation.

• Visual acuity for reading computer screens and documents.

• Ability to communicate effectively in person, by phone, and via video.

• Occasional standing, walking, and reaching for files or supplies.

• Occasional lifting of up to 15 pounds (files, office supplies, equipment).

• Ability to commute to office location as required.

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.

Pay Transparency, Budgeted Range
$130,000—$150,000 USD

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Science - Minded, Patient - Focused.

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most.

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.

• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.

• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.

• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

• Be bold in our vision & brave in our execution. 

• Communicate directly, with empathy. 

• Do what we say we're going to do.  

• Be adaptable to change.  

• Operate with a bias for action.  

Benefits include:

• Paid Time Off (PTO)

• Health, Dental, Vision and Life insurance

• 401k Retirement Savings Plan

• Employee Discounts

• Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.