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IT Enterprise Architect

Adaptivebiotechnologies

Remote (WFH) Remote permanent

Posted: January 8, 2026

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Job Description

At Adaptive, we’re Powering the Age of Immune Medicine. Our goal is to harness the power of the adaptive immune system to transform the way diseases are diagnosed and treated.

As an Adapter, you’ll have the opportunity to make a difference in people’s lives. With Adaptive, you’ll create a career highlight through collaboration with bright, curious colleagues working at the apex of innovation and application.

It’s time for your next chapter. Discover your story with Adaptive.

Position Overview

The IT Enterprise Architect provides solution architecture leadership across cloud (with a strong emphasis on Microsoft Azure), data center, networks, storage, identity, ensuring platforms are secure, scalable, observable, and cost-efficient. The role sets standards and patterns, leads critical solution designs, and governs delivery through design reviews and technical leadership. They will work closely with business units and IT engineers and managers to design, develop, and integrate computer systems, review existing environments to identify areas for improvement and monitoring the outcome of new or upgraded systems. Responsibilities include tracking the full IT technology portfolio and developing a multi-year roadmap, analyzing systems and applications throughout the ecosystem, making recommendations at a program, project and collective IT organization levels, evaluate system design, and create and maintain procedures, and processes as required to deliver proven solution designs. The IT Enterprise Architect is responsible to design and plan for operations support, monitoring, security, and management in addition to core functional requirements. The IT Enterprise Architect reports to Enterprise Architecture function to represent IT interests and concerns, align solution designs and delivery to the enterprise architecture direction, and help to govern technology standards. The IT Enterprise Architect is integral to service delivery and enablement.

Azure expertise is foundational to this role, including Azure Landing Zones, network architecture, and Azure-native platform services.

Key Responsibilities and Essential Functions

• Partner with the various business units to identify current concerns and needs and potential solutions. Provides guidance and support on how best to implement the recommended solution based on best practice and current environment and team structure.

• Define current/future state architectures and long-term roadmaps aligned to business goals

• Model TCO, right-size capacity, and implement cost controls and FinOps practices

• Lead end-to-end design for initiatives (e.g., micro-segmentation, WAF/API gateway, observability, backup/DR etc.) leading to modernization of existing IT solutions

• Publish reference architectures, ADRs, guardrails, and golden paths, gap/drift analysis and deviation handling

• Partner with engineers to transition designs to build; validate via PoCs; de-risk with modeling phased rollouts

• Communicate alternatives, risks, and tradeoffs to execs and teams and influence decision-making

• Provide mentorship and coach engineers to elevate engineering practices and design thinking

Position Requirements (Education, Experience, Other)

Required

• Bachelor’s degree in technology or computer science and 12+ years of related experience

• Master’s degree and 10+ years of related experience

• Three years of work experience in IT solution design and architecture

• Three years of hands-on cloud solution design and deployment

• Excellent communication, facilitation, and documentation skills, able to translate complex technical concepts for diverse audiences.

• Strong proficiency in IT architecture, solution design, systems thinking, and cross-platform integration.

• Advanced cloud architecture expertise with a focus on Microsoft Azure (Landing Zones, governance, networking), with familiarity in AWS as a plus.

• Deep expertise of hybrid networking and identity/IAM, including Entra ID, SSO/OIDC/SAML, Conditional Access, and workload identity patterns.

• Hands-on experience with security architecture, including WAF, API security, segmentation, PAM/PIM, secrets management, and Azure Key Vault / KMS.

• Strong grasp of observability and reliability engineering, including logging, metrics, tracing, SLO/SLI design, DR/BCP, and operational readiness.

• Proficiency in Infrastructure-as-Code and automation (Terraform, Bicep, CI/CD pipelines).

• Broad knowledge of understanding of AI Platforms and related IT principles including understanding of agentic frameworks, infrastructure aspects related to Generative AI models and agents.

Preferred

• Six years of solution design and implementation experience

• Cloud architecture certification from one or more public cloud providers

• TOGAF certification

• Infrastructure as Code tool experience

• Full stack monitoring and advanced operations management experience

• Experience with risk management and compliance frameworks (SOC2, ISO, HIPAA/PHI as applicable).

Working Conditions

General office working conditions involving sitting, standing, and long periods of time using computers. May require occasional off hours work to support implementation or testing needs.

#LI-Remote

Compensation

Salary Range: $144,600 - $217,000

Possible “other compensation” elements to include:

• equity grant

• bonus eligible

ALERT: Malicious groups posing as Adaptive employees have recently used fraudulent email aliases to extend employment offers, provide fake documents, and request sensitive personal and financial information. Legitimate Adaptive employment opportunities are initiated through our careers page and extended after multiple interviews with verified employees. Adaptive does not ask new hires to purchase anything out-of-pocket, including home office supplies and equipment.

Interested in this position, but don’t meet all the requirements? Adaptive is committed to building diverse, equitable, and inclusive teams across our organization. Please consider applying even if your experience doesn’t match all the qualifications; you may be the exact candidate we’re searching for!

Adaptive is not currently sponsoring candidates requiring work authorization support for this position.

Adaptive’s posted compensation information includes a base salary (or hourly rate) range and summary of other available total compensation. The base salary range represents a minimum-to-maximum salary (or hourly rate) available to candidates upon extension of offer. Base salary is thoughtfully considered upon offer and is determined through multiple evaluation checks throughout the interview process, including: a candidate’s ability to meet minimum qualifications (skills/experience/education), a candidate’s ability to thoughtfully address preferred qualifications, current market conditions, and internal pay equity. Listed base salary is exclusive of bonus, commission, equity, differential pay, benefits, and other incentives.

Adaptive's benefits at-a-glance.

Adaptive Biotechnologies is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against based on disability. Please refer the “Know Your Rights: Workplace Discrimination is Illegal” Poster for more information. If you’d like to view a copy of the company’s affirmative action plan or policy statement, please email [email protected].

If you have a disability and you believe you need a reasonable accommodation to search for a job opening or to submit an online application, please e-mail [email protected]. This email is created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response.

NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners who have active agreements with Adaptive. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.

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