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HR Operations Specialist

Confidential

Durham, North Carolina Hybrid permanent

Posted: January 30, 2026

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Quick Summary

The HR Operations Specialist will support and manage the day-to-day human resources operations of the company and be responsible for executing core HR processes and ensuring accuracy, consistency, and compliance.

Job Description

Job Title: HR Operations Specialist   

Department: Human Resources     

About Pelthos:

Pelthos Therapeutics is a bio-pharmaceutical company committed to commercializing innovative, safe and efficacious therapeutic products to help patients with unmet treatment burdens. For more information, please visit our website at www.pelthos.com or follow us on LinkedIn and X. 

Job Summary:

The HR Operations Specialist will support and manage the day-to-day human resources operations of the company and be responsible for executing core HR processes and ensuring accuracy, consistency, and compliance across the employee lifecycle. This is a highly detail-oriented, hands-on role is ideal for someone who enjoys managing data, administering processes, improving workflows, and serving as a reliable operational partner to HR leadership.

 

Essential Duties & Responsibilities:

HR Operations & Employee Records

Maintain and update the HRIS with employee data, changes, and supporting documentation

Track and administer employee changes, including promotions, compensation updates, and status changes

Maintain accurate, up-to-date, and confidential employee files in compliance with company policies and regulations

Onboarding & Offboarding

Coordinate and administer new hire onboarding, including documentation, HRIS entry, and orientation logistics

Ensure accurate and timely offboarding, including exit documentation and system updates

Recruiting & Hiring Support

Post job openings and manage applicant tracking

Coordinate and schedule interviews with candidates and hiring managers

Prepare and issue offer letters and related employment documentation

Benefits Administration

Support benefits enrollment, life event changes, and employee inquiries

Coordinate with benefits providers and brokers as needed

Assist with open enrollment preparation, communications, and data reconciliation

Performance, Compensation & Compliance Support

Support the administration of performance review cycles, including tracking timelines, completion, and documentation

Support HR compliance activities, audits, and required employee training tracking (e.g., I-9s, policy acknowledgments, required trainings)

Data, Reporting & Process Improvement

Use Excel to track, audit, and reconcile HR data, including headcount, employee changes, and benefits information

Ensure data accuracy and consistency across HR systems and reports

Identify opportunities to improve HR processes, documentation, and operational efficiency as the company scales

Ability to travel up to 10%

Other duties as assigned

 

Experience & Qualifications:

Bachelor’s degree with 2–4 years of experience in an HR Operations or HR Coordinator role

Experience supporting multiple HR functions across the full employee lifecycle

Strong Excel skills, including working with spreadsheets, formulas, data validation, and basic reporting

Exceptional attention to detail and a high level of accuracy in data entry and documentation

Experience working with HRIS platforms and maintaining employee records

Ability to handle confidential and sensitive information with discretion and professionalism

Strong organizational, time management, and communication skills

Comfortable working in a lean, fast-growing environment

Preferred:

Experience in pharmaceutical, biotech, or other regulated industries

Experience supporting benefits administration and compliance activities

 

Physical & Environmental Requirements:

The essential functions of this position include:

Lift up to 25lbs on an occasional basis

Stand, walk, sit on a frequent basis

Reach, hands and arms on a frequent basis

Communicate using hearing and speech on a frequent basis (in-person and/or virtual)

Use vision (color difference, depth perception) on a frequent basis

 

These functions must be performed safely and effectively, without posing a direct threat to the employee or others, with or without reasonable accommodation.

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