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Histotechnologist I

Natera

San Carlos, CA (Natera - SF Bay Area) permanent

Posted: January 28, 2026

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Quick Summary

Performs histological preparations for Signatera Whole Exome/Genome Sequencing laboratory with little to no errors.

Job Description

POSITION SUMMARY:

Performs histological preparations for Signatera Whole Exome/Genome Sequencing.

We offer several shifts that are accommodating to most schedules.

PRIMARY RESPONSIBILITIES:

• Perform histological preparations for the tissue whole exome sequencing laboratory with little to no errors

• Duties may include but not limited to: preparation of tissues, stained slides, microdissection, and supporting workflow tasks

• May independently perform testing, reagent and equipment preparation after completion of training and competency.

• Participates in validations

• Performs qualifications of reagents

• Monitors and performs case management; ensures all cases are processed within department TAT goals and investigates sample processing issues

• Actively participate in EH&S initiatives such as safety audits

• Participates in updating and creating Standard Operating Procedures

• May serve as a general supervisor (Depending on education and years of experience) and perform competencies

• Has an understanding of equipment and process troubleshooting

• Document all corrective actions taken when test systems deviate from the established performance specifications as needed. Escalates protocol deviation to supervisor.

• Provides general oversight of personnel and the daily operations in the lab. Provides guidance to new team members.

QUALIFICATIONS

• A bachelor's, or higher, degree in a histotechnician program
OR

• A bachelor's, or higher, degree in one of the chemical, or biological sciences, including a combination of thirty (30) hours in biology and chemistry; and, either one of the following conditions:
-one year of experience and/or training in histology within the past 5 years OR
-completion of a course of training of at least nine months in an histotechnician program
A copy of the degree is required at time of hire; the degree must either be from the US or equivalent to a US
bachelor's degree.
• HTL (ASCP) required
• Science - related degree preferred
• 0-2 years of related experience

KNOWLEDGE, SKILLS, AND ABILITIES:


Excellent written and oral communication skills.


Able to accurately understand and convey information to team members.


Detail-oriented. Ability to think broadly about the importance of information.


Ability to work independently.

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:


Long-term equity awards


Comprehensive health benefits (medical, dental, vision)


401(k) with company match


Generous paid time off and company holidays


Additional wellness and work-life benefits

Compensation Range
$28.91—$36.14 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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