Head of Process Analytical Technology - Mammalian Platform

Job Title: Head of Process Analytical Technology - Mammalian Platform

Location: Framingham, MA

About Sanofi:
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

About the Job

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

Are you ready to help create the future of biomanufacturing? At Sanofi, we strive every day to Take the Lead to innovate for patients with novel therapeutics and manufacturing technology. Your leadership skills and expertise in Process Analytical Technology (PAT) could be a key enabler that helps us realize that future together.

The Mammalian Platform (part of Sanofi R&D) is responsible for the development, scale-up, and transfer of upstream and downstream processes and their control strategies for clinical and commercial manufacturing of therapeutic proteins produced from mammalian cell lines. In addition, the department actively invests in developing and implementing new technologies related to integrated and continuous biomanufacturing, process analytical technology (PAT), high throughput process development, and modeling. Ultimately, our goal is to design robust processes that produce safe and effective medicines as efficiently as possible.

We are looking for candidates to lead our Process Analytical Technology activities across the Mammalian Platform including applications for both cell culture and purification processes. This individual should be able to combine innovation leadership skills with technical expertise to continuously evolve and lead teams in the delivery of our Process Analytical Technology roadmap. The incumbent will lead in a matrixed structure, leveraging resources across the platform’s global footprint in both the United States (Framingham, MA) and France (Vitry) while representing the platform at the interface with our Commercial Manufacturing and Supply (M&S) organization.

This role will report to the Global Head of Purification Development, providing a direct link to Mammalian Platform leadership to support sustained innovation and technology implementation in both clinical and commercial manufacturing applications.

Main Responsibilities:

• Lead the development and implementation of Process Analytical Technology for the Mammalian Platform, including cell culture and purification applications

• Drive the design and evolution of our Process Analytical Technology roadmap to enable near-term implementation and long-term disruptive innovation

• Represent the Mammalian Platform for PAT-related topics, interfacing with Commercial Manufacturing and Quality, as well as other Platforms within R&D (Microbial, Genomic Medicines, mRNA, Vaccines, Synthetics)

• Engage relevant stakeholders across R&D and Commercial Manufacturing to ensure resources, budget, and implementation risk are adequately managed and communicated

• Identify opportunities to improve our process development strategies and manufacturing approaches through the application of PAT

• Act as a PAT champion across the Sanofi R&D and Manufacturing network

• Mentor scientists across sites and teams fostering their career development and professional growth

About You

Basic Qualifications:

• PhD. in Biochemical Engineering, Chemical Engineering, Analytical Chemistry, Physics, Bioengineering, Electrical Engineering, or related fields with at least 7 years of experience or a M.S. with at least 11 years of relevant experience or a B.S. with at least 12 years of relevant experience

• Relevant industrial experience and/or academic experience in Process Analytical Technology development

Preferred Qualifications:

• Experience with spectroscopic Process Analytical Technology (Raman, Near-Infrared, Mid-Infrared, Fluorescence, UV-Vis) techniques

• Experience with online or inline analyzers for Process Analytical Technology applications (HPLC, UPLC, LCMS, DLS, MALS) and auto-sampling techniques

• Understanding of PAT-enabling digital architecture and its application in manufacturing settings (SynTQ, SIMCA-Online, Distributed Control Systems)

• Familiarity with relevant Regulatory and Quality frameworks related to control strategy, method qualification, process validation, and data integrity

• Understanding of upstream and downstream unit operations, process development, and technology transfer

• Understanding of product quality attributes of therapeutic proteins (antibodies, multi-specific antibodies, fusion proteins, enzymes)

• Ability to lead a diverse, cross-functional, cross-site matrixed team

• Excellent communication skills in both written and oral settings

• High level of scientific curiosity and innovation mindset

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$178,500.00 - $257,833.33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.