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Head of Commercial Excellence and Operations

10xgenomics

Pleasanton, California, USA HQ (USA.CA.Pleasanton - Stoneridge (Office)) Remote permanent

Posted: February 10, 2026

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Quick Summary

The Head of Commercial Excellence and Operations is responsible for developing and managing the commercial framework that drives predictable revenue.

Job Description

Role Purpose

The Head of Commercial Excellence and Operations is responsible for developing and managing the commercial framework that drives predictable revenue. This leader owns commercial process adoption, pipeline management, and forecast governance - from executive-level reviews to frontline manager coaching and individual contributor execution.

This leader defines the organization's commercial methodology through standardized processes, enablement programs, and strategic planning mechanisms. They will partner closely with Commercial Technology and Business Analytics teams to ensure the commercial infrastructure supports long-term growth.

What you will be doing:

Commercial Process Management

• Define and continuously improve the commercial methodology, including stage definitions, handoffs across roles, and required documentation.

• Drive field adoption through standardized commercial operating procedures, inspection routines, and manager coaching toolkits.

• Establish and lead the commercial operating rhythm (e.g., pipeline reviews, deal clinics, and quarterly business reviews).

Funnel, Pipeline & Forecast Governance

• Standardize commercial definitions for pipeline hygiene, funnel metrics, and forecasting categories.

• Lead the forecast governance from executive-level reporting to frontline inspection.

• Partner with Business Insights teams on commercial analytical inputs while maintaining ownership of the underlying process and commitments.

Commercial Planning & Field Productivity

• Oversee territory design, quota allocation, and incentive compensation governance in collaboration with cross functional stakeholders.

• Ensure account and territory planning activities are practical, adopted by the field, and measurable.

• Oversee deal desk support and commercial channel operational mechanisms.

Commercial Enablement & Commercial Education

• Oversee the Commercial Enablement & Education functions to drive behavioral change and field effectiveness.

• Ensure onboarding, certifications, and training programs align with established commercial processes and performance goals.

• Establish closed-loop feedback: commercial enablement programs → behavior adoption → performance impact → iteration.

Minimum Requirements:

Qualifications

• 8+ years of experience in Commercial Operations, Sales Enablement, Revenue Operations, or related roles

• 4+ years of leadership experience, including building and managing teams.

• Demonstrated success in designing and scaling enablement programs (playbooks, content, deal desk, SOPs, pipeline/forecast management).

• Experience in process mapping, workflow optimization, or formal project/process management certification (e.g., PMP, Lean Six Sigma) is a plus.

• Strong commercial acumen and experience supporting customer-facing teams in complex B2B/scientific sales environments.

• Exceptional communication and stakeholder management skills; able to influence and drive alignment across functions.

• Bachelor’s degree in Business, Marketing, Life Sciences, or related field required

Preferred Qualifications:

• Strong preference for experience in life sciences, biotechnology, or scientific instrumentation.

• MBA or advanced scientific/business degree preferred. Direct field sales and/or field sales management experience

*While we prefer candidates based in the San Francisco Bay Area, we will consider remote candidates*

#LI-AR1

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

Pay Range
$278,200—$376,400 USD

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

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