Head of AI/ML Engineering

Role Overview

The Head of AI Engineering is a technology and entrepreneurial Generative AI engineering leader who will build and scale our new Generative AI and ML Solutions team. You will be responsible for building and executing our Generative AI engineering strategy, governance, and delivery across the organization while aligning them with the organization’s strategic goals of using AI to improve productivity, efficiency, and experience. In this role, you will be at the forefront of the generative AI change, leading a world-class engineering organization that designs and implements cutting-edge solutions to solve Natera’s AI/ML challenges. As part of this role, you will join Natera’s AI office as a key executive member and will be accountable for building and executing an AI solutions delivery plan in alignment with business needs to unlock transformative business value

Key Responsibilities

AI Technical Strategy & Architecture

•
Own the end-to-end technical vision for the entire AI/ML platform, from data ingestion, MLOps, model serving, fine-tuning, foundation model training, RAG, and agentic applications.

•
Make the critical "build vs. buy vs. open-source" decisions that balance speed, cost, and long-term defensibility

Team Leadership & Talent Development

•
Recruit, hire, mentor, and retain an elite team of T shaped AI engineers, applied ML engineers, data scientists, and platform engineers.

•
Design a rigorous hiring process to find "unicorn" talent and foster a culture of continuous learning and excellence.

AI/ML Platform Lifecycle Ownership

•
Design, build, and scale an AI/ML platform that provides standardized tooling, infrastructure, and workflows for LLM training, fine-tuning, retrieval-augmented generation (RAG), AI orchestration, and deployment.

•
Develop reusable components and services (e.g., vector databases, prompt libraries, agent frameworks, model registries, evaluation pipelines, safety/guardrail modules) to accelerate delivery of AI solutions across product engineering teams.

•
Ensure reliability, scalability, and compliance of the AI/ML platform by implementing robust observability, governance, and cost-optimization strategies tailored for large model serving and API consumption.

Execution & Delivery

•
Partner with business and product owners to identify, design, and implement high-impact AI solutions that drive measurable outcomes, ensuring alignment with strategic priorities.

•
Own the full lifecycle of AI solutions — from prototyping and deployment through ongoing monitoring, maintenance, and enhancements — ensuring solutions remain accurate, performant, and relevant as business needs evolve.

•
Continuously improve deployed AI systems by incorporating feedback, retraining models, and updating components to adapt to changing data, regulatory requirements, and operational realities.

Operational Excellence

•
Implement robust processes for quality assurance, model governance, and performance monitoring.

•
Drive adoption of a combination of hyper-scaler AI services and specialized cloud native AI solutions to accelerate time-to-market.

•
Lead cost observability and management initiatives to optimize AI infrastructure and usage at scale.

•
Ensure compliance with AI Governance policies

Strategic Alignment

•
Serve as the primary bridge between business stakeholders and the AI Office.

•
Ensure AI product roadmaps align with Natera’s broader AI vision and business objectives.

•
Champion a culture of responsible AI adoption, ensuring ethical, compliant, and explainable use of AI.

Cross-Functional Collaboration

•
Translate business needs into actionable technical requirements for engineering and business teams.
Collaborate with security, regulatory, compliance, and legal to ensure solutions meet security and regulatory standards.

•
Partner with AI Governance and Change Enablement leads to ensure trust, fairness, and adoption across the organization.

Qualifications

Required:

•
15+ years of experience in an engineering leadership role in AI, ML, or data science

•
Expertise in Generative AI, including LLMs, prompt engineering, RAG, fine-tuning, training, and evaluation methodologies.

•
Proven track record of delivering production-grade AI solutions in customer-facing and internal products especially using LLMs and ML models

•
Strong understanding of production software engineering best practices, CI/CD, testing, observability, error handling, and security.

•
Experience with AWS based AI services and other specialized AI platforms (e.g., AWS Bedrock, Snowflake AI, Google AI, OpenAI, xAI).

•
Demonstrated ability to optimize AI model performance and costs for large-scale deployments especially LLMs.

•
Exceptional communication and cross-functional collaboration skills.

•
Excellent stakeholder engagement, prioritization, and communication skills.

Preferred:

•
Advanced degree (MS/PhD) in Computer Science, AI/ML, engineering or related field.

•
Experience in healthcare, pharma, diagnostics, or other regulated industries.

•
Familiarity with AI governance frameworks, bias detection, explainability, and compliance (e.g., HIPAA, CLIA, FDA).

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$217,400—$271,800 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page