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HCP Marketing Lead

Zenasbio

Waltham, MA (USA) Hybrid permanent

Posted: December 18, 2025

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Job Description

Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines our experienced leadership team with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include a preclinical, potentially best-in-class, oral, IL-17AA/AF inhibitor, and a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor.

We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation!

Position Summary:

Zenas is seeking a seasoned, dynamic commercial leader with extensive I&I experience and US Market understanding to lead the Brand Marketing strategy and activities. Reporting to the VP Head of Marketing, the HCP Marketing Lead will drive the marketing strategy for Obexelimab, focusing on the launch of its 1st indication in IgG4-Related Disease, setting a customer-centric vision and delivering high performance standards. This leader will oversee all aspects, from brand positioning and messaging to resource prioritization, ensuring alignment with other cross-functional partners. This is a critical role that will be instrumental in the Company’s continued success.

Key Responsibilities:

• Lead the development of Obexelimab brand strategies, focusing on product positioning, messaging, and market differentiation.

• Lead Cross-functionnal launch readiness governance and execution for Obexelimab in IgG4-RD

• Represent US Marketing on the Obexelimab US Brand Team, collaborating on strategies, messaging, and materials to ensure consistency strategic alignment across function.

• Ensure strong collaboration between the US Marketing team and counterparts on cross-functional teams, including Sales, Access & Trade, Strategic Engagement, Analytics, Medical Affairs, Compliance, Legal and Regulatory and Patient Support Services.

• Utilize market and customer insights to inform key business decisions and refine brand and customer strategies.

• Establish core messaging for a diverse customer base, including HCPs & KOL.

• Lead the creation of HCP marketing assets (disease education and promotional materials), including development, review, approval that aligns with brand positioning, messaging, and regulatory guidelines

• Lead the creation of a Market Development strategy including the development, review and approval of all materials associated with market development activities

• Collaborate closely with Strategic Engagement to collect relevant insights for the Brand Strategy, and build and execute the market development plan (Congress, Ad board, Speaker Bureau…)

• Lead customer segmentation efforts to optimize outreach and engagement across channels and ensure precise targeting.

• Leverage data and analytics to allocate marketing budget effectively across channels and audience segments, ensuring optimal utilization of marketing budgets.

• Prioritize investment opportunities and secure budget approval from senior leadership, advocating for resources to support strategic initiatives.

• Champion cross-functional teamwork and team engagement, fostering a culture of continuous learning, growth, and diversity.

Qualifications:

• Bachelor’s degree required; advanced degree in business or life sciences preferred.

• Deep marketing experience required. I&I &/or Rare Diseases experience preferred.

• Deep understanding of the US Market Dynamics

• Exceptional communication and analytical skills, with a focus on high-impact execution and results.

• Proven success in customer-centric marketing strategy development and cross-functional leadership

• Strong project management skills with the ability to manage multiple projects simultaneously while meeting tight deadlines

• Established Marketing skills.

• HCP, Account, & Digital marketing experience with multiple brands. Demonstrated expertise in omnichannel, modular marketing and content / channel strategy.

• Field experience will be a plus

• Ability to travel up to 33%.

#LI-Hybrid

The position is eligible for a competitive compensation and benefits package.

Zenas is committed to fair and equitable compensation practices. The base salary pay range for this role is $217,600 to $272,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.

Zenas believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Zenas’ competitive total rewards strategy that also includes annual performance bonus, equity, full range of benefits and other incentive compensation plans.

Zenas BioPharma is proud to be an equal opportunity employer. We are committed to fostering an environment where diversity is valued. All qualified applicants will receive consideration for employment based on merit, qualifications and the needs of the business.

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