Global Medical Affairs Inhaled COPD Leader Evidence Confidence

The Global Medical Affairs Leader (GMAL) reports directly to the Medical Head of Inhaled COPD and plays a vital strategic business role. As an experienced leader in Medical Affairs, this individual is responsible for developing medical and promotional advocacy activities for our COPD products.

The GMAL's influence extends globally across AstraZeneca, participating in the Global Medical Team and the Global CFT team, and collaborating with medical personnel in key markets and regions. The Global Medical Affairs Lead (GMAL) for Breztri/Trixeo will shape and execute the global medical strategy. This role will drive medical confidence and advocacy, support country-level guideline pull-through and GDMT acceleration, lead the Next-Generation Product (NGP) Breztri transition and orchestrate omnichannel and AI-enabled initiatives. The GMAL will partner cross-functionally to ensure scientific excellence, external credibility, and consistent global-to-local implementation across priority markets.

Essential Duties and Responsibilities:

• Medical Strategy and Leadership: Provide global oversight of medical affairs for Breztri/Trixeo, ensuring strategic alignment with therapeutic priorities, lifecycle management, commercial objectives, and scientific standards.

• Evidence Generation, Publications and Dissemination: Oversee real-world evidence (RWE), health economics and outcomes research (HEOR), and Phase 4 post-approval studies to fill priority evidence gaps. Ensure scientific publications, congress participation, and data communications are both timely and of high quality.

• Medical Confidence: Establish external credibility by disseminating robust evidence, engaging thought leaders, and facilitating scientific dialogue to reinforce Breztri’s clinical value proposition.

• Guideline and GDMT Support: Collaborate with country medical teams to support the adoption and execution of guideline-driven initiatives and accelerate GDMT (Guideline-Directed Medical Therapy) implementation; supply scientifically validated resources and frameworks to ensure consistency with local healthcare practices.

• NGP Breztri Transition: Manage cross-regional planning and execution of the NGP transition throughout the EU, while preparing for upcoming launches. Coordinate integrated evidence generation, anticipate label changes as needed, and deliver comprehensive education for healthcare professionals to optimize launch and post-launch impact.

• Global-to-Local Enablement: Develop consistent global medical narratives, educational platforms, and toolkits; mentor and align regional and country medical teams on execution standards and key performance indicators.

• Medical Governance and Compliance: Maintain rigorous scientific integrity, uphold ethical standards, and ensure compliance across medical activities, including both promotional and non-promotional reviews.

• Cross-Functional Collaboration: Work collaboratively with R&D, Commercial, Market Access, Regulatory, Safety, and Digital/Analytics to achieve integrated planning, seamless execution, and continuous improvement informed by market insights.

Essential for the role:

• Demonstrate in-market or regional medical affairs expertise in Respiratory, translating scientific evidence and market dynamics into actionable medical strategies and advocacy roadmaps tailored to local needs; successfully led advocacy initiatives in a local context.

• Build and maintain effective relationships with key external experts (KEEs), patient advocacy groups, healthcare organizations, payers, and healthcare systems, resulting in collaborative initiatives and improved patient outcomes.

• Demonstrated ability to build internal and external networks across geographies and cultures, developing and implementing confidence and advocacy strategies in a global context.

• Generate and analyze substantial clinical and real-world evidence, including successful leadership of Phase 2, 3, or 4 clinical trials, and driving impactful RWE projects such as world-class registries and label-enhancing data initiatives.

• Cultivate strong working relationships with global thought leaders, key experts, professional societies, and other healthcare organizations, contributing to high-impact collaborations and industry advancement.

• Communicate complex scientific concepts clearly and effectively, delivering impactful presentations and ensuring high-quality, objective data communication.

• Apply AI/ML-driven insights and omnichannel orchestration to develop measurement frameworks, exemplified by the successful implementation of an AI-powered healthcare initiative.

• Exhibit strong leadership and project management skills, with a proven ability to drive cross-functional initiatives and implement transformative healthcare projects across geographies and regulatory contexts, including leading multi-country clinical trials and guiding teams through change.

Desirable for the role:

• Doctoral level degree: MD, PhD, or PharmD

• Expertise in advocacy activities, sustainability and next-generation propellants is desirable

• Relevant experience beyond Medical Affairs (e.g. in a marketing/R&D/Market Access/ CI role) is a nice to have.

• Experience launching new products or indications, and in developing and launching medicines in key geographies (e.g. US, China, Japan)

• Expertise in clinical and implementation research

Are you ready to bring new insights and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours. Apply today.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

The annual base pay for this position ranges from $241,602 - 289,922 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus

Date Posted

24-Mar-2026

Closing Date

23-Apr-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.