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Global Commercial Head, Bispecifics

AstraZeneca

US - Gaithersburg - MD permanent

Posted: January 14, 2026

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Job Description

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We are committed to leading a revolution in oncology to redefine cancer care and address the unmet needs of patients around the world. We are following the science to understand cancer and all its complexities so that we can discover, develop and deliver life-changing treatments and increase the potential for cure. The Oncology business is the fastest growing team within AstraZeneca and across the industry. Through our relentless quest for innovation, we have created one of the most diverse portfolios and pipelines in the industry. We deliver on the promise of our pipeline through launch excellence, commercial effectiveness and maximizing the lifecycle. We have an exciting opportunity for a Global Commercial Head, Bispecifics to join our Global Oncology Franchise Team, advancing AstraZeneca’s mission to transform cancer care and improve patient outcomes. This position reports into the VP, Global Franchise Head, Bispecifics. In this pivotal role, you will shape commercial strategy and lead launch readiness for our lead bispecific agent, which is being developed across a number of indications and tumor types. You will be responsible for developing and driving the overall commercialization plans across indications and tumor areas, by collaborating directly with Global Product Team (GPT)/ R&D Franchise leadership teams, Medical, Market Access, Diagnostics, Regional teams, country teams and other OBU functions, as well as Tumor Council committees. Leading the Integrated Business Team across regions and playing a leading role on GPT, you will oversee the planning and execution of commercialization efforts, ensuring teams are aligned and effective across regions. This leadership position is central to ensuring AstraZeneca brings cutting-edge immuno-oncology therapies to cancer patients worldwide. What You'll Do: Drive and execute global commercialization plans for our lead Bispecifics asset across tumors, planning for a cascade of launches in quick succession. Partner with GPT, IBT, Medical, Market Access, Diagnostics, and regional teams to deliver launch and lifecycle objectives. Champion commercial priorities in cross-functional teams, governance meetings, and external engagements. Develop, implement, and evolve global brand strategies to ensure launch readiness and sustained growth. Work with core country teams, with strong emphasis on the US, to align and deliver successful commercialization. Build sustainable pricing and access models with internal and external partners for target indications. Shape global and in-market commercialization capabilities and share best practices for Bispecifics Drive market-shaping initiatives, partnerships, and innovative approaches to patient care and value creation. Manage and inspire the global marketing team, fostering collaboration and high performance. Engage and influence senior internal and external stakeholders to accelerate business priorities. Minimum Qualifications: Bachelor's degree in a relevant field, such as business or life sciences. 10+ years of experience in pharmaceutical development and commercialization. Extensive expertise across drug development and commercialization in oncology. Proven experience and accountability for business success in the US healthcare market. Experience in global commercial strategy, launch readiness, long-term planning, and HTA validation. Experience in working with R&D organizations to shape global strategy. Ability to work in ambiguous environments and influence without authority Established proficiency in guiding complex and uncertain projects with agility, independence, and a strategic attitude. Effective analytical, organizational, and communication skills, with proficiency in using insights to drive brand success. Keen understanding of the strategic and operational considerations for in-market success and proven ability to negotiation trade-offs when there are competing priorities Excellent collaboration and partner engagement skills, with the capacity to work across scientific and commercial teams. Proven leadership in building effective teams and leading cross-functional, matrixed organizations. Preferred Qualifications: MBA, PhD, or advanced degree in a related field. Sales or customer-facing experience. Experience in both market and global commercial organizations. Management experience leading diverse teams. In-depth knowledge of global healthcare regulations, compliance, and pharmacovigilance. This position is based at our Gaithersburg, MD campus (US Headquarters for Global Oncology Business Unit). When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and bold world. AstraZeneca offers an environment where you can thrive by working with new drugs, digital approaches, and ever-changing environments. Our pioneering value-based agreements and Innovative Value Strategy solutions lead the way in the industry. We are driven by our determination to ensure the value of our medicines is realized. Our dynamic environment encourages creativity in designing strategies and innovative access solutions. We thrive on co-creation and draw on diverse perspectives to overcome challenges. Join us to be part of a team that is passionate about making a meaningful impact on patient outcomes. Ready to make a difference? Apply now to join our team! The annual base pay for this position ranges from $270,221 - 405,332 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 14-Jan-2026 Closing Date 05-Feb-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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