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Global Commercial Head, Bispecifics

AstraZeneca

US - Gaithersburg - MD permanent

Posted: May 11, 2026

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Quick Summary

We are seeking a Global Commercial Head, Bispecifics to join our team and contribute to our efforts to transform cancer care. The role requires strong leadership and entrepreneurial spirit, with a deep understanding of oncology and a passion for delivering life-changing treatments.

Job Description

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We are focused on leading a revolution in oncology to redefine cancer care and address the unmet needs of patients around the world. We are following the science to understand cancer and all its complexities so that we can discover, develop and deliver life-changing treatments and increase the potential for cure.

The Oncology business is the fastest growing team within AstraZeneca and across the industry. Through our relentless quest for innovation, we have created one of the most diverse portfolios and pipelines in the industry. We deliver on the promise of our pipeline through launch excellence, commercial effectiveness and maximizing the lifecycle.

At AstraZeneca, our franchise teams are pivotal in driving launch and commercial effectiveness, setting direction to shape the cancer care landscape and empower care teams. The Bispecifics franchise is focused on the next wave of immuno-oncology (IO) bispecific therapies that are designed to empower the immune system to more effectively recognize and kill cancer cells. We seek a highly skilled Global Commercial Head to join our leadership team and guide the commercialization strategy for a novel IO Bispecific asset. This strategic role is integral to our Global Commercial Franchise Team in the Oncology Business Unit, advancing our mission to transform cancer care worldwide.

Accountabilities:

• Develop and drive a comprehensive global commercialization strategy for a Bispecifics brand, enhancing portfolio value across multiple tumor areas and indications.

• Collaborate with Global Product Team (GPT), R&D Franchise leadership, and global cross functional teams including Insights and Analytics, Medical Affairs, Market Access, Diagnostics, and other vital functions, ensuring alignment and effective execution of short and long term strategic initiatives.

• Lead the Integrated Brand Teams, partnering with Regional and Country teams, to craft and implement a unified global brand strategy, develop commercialization plans and deliver launch excellence.

• Shape and set in motion cutting-edge commercialization strategies and programs, ensuring effective launch readiness.

• Engage and partner with Regional/Country teams to facilitate knowledge sharing and strategy optimization across various markets.

• Provide strategic commercial input and influence LCM plans and revenue forecasts, guided by robust customer insights and commercial judgment.

• Nurture a high-performing matrixed team, fostering innovation, collaboration, and strategic thinking.

• Represent the Bispecific business perspectives in cross-functional forums and senior executive meetings, advocating commercialization priorities.

• Champion the co-development of patient-centric solutions, external partnerships, and sustainable pricing and access strategies.

Essential Skills & Experience:

• Bachelor’s degree in a relevant field (business or life sciences).

• Over 10 years of experience in pharmaceutical development and commercialization, with proven expertise in strategic marketing and launch excellence.

• Strong ability to collaborate across scientific and commercial teams, demonstrating strategic and analytical skills.

• Demonstrated success in pre-launch and launch excellence, with robust insight generation and competitive landscape analysis capabilities.

Preferred Skills & Experience:

• MBA or advanced degree in a related field.

• Previous sales or customer-facing experience.

• Management experience with diverse teams.

• Ability to thrive in ambiguity and lead innovative projects with strategic foresight.

This position is based at our Gaithersburg, MD campus, headquarters for the US and Global Oncology Business Units. When we put diverse teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and bold world.

AstraZeneca offers an environment where you can thrive by working with new drugs, digital approaches, and ever-changing environments. We are driven by our determination to ensure the value of our medicines is realized and look for opportunities to transform care and address care gaps, across the treatment paradigm. Our dynamic environment encourages creativity in designing strategies and developing innovative solutions. We thrive on co-creation and draw on diverse perspectives to overcome challenges. Join us to be part of a team that is passionate about making a meaningful impact on patient outcomes.

The annual base pay for this position ranges from $231,988-$347,983 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

11-May-2026

Closing Date

31-May-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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