Global Commercial Director Haemotology

The Global Commercial Director will be a key member of the Global Calquence Astra Zeneca Team, accountable for shaping and delivering the global commercial strategy in Chronic Lymphocytic Leukemia (CLL).

This role will lead the CLL indication across all lifecycle stages, with a strong focus on driving the transformation of the treatment paradigm, maximizing the value of Calquence, and ensuring best-in-class execution across markets.

Reporting to the Global Commercial Head, Calquence, the role works in close partnership with global, regional and country teams, as well as cross-functional stakeholders (Medical, Access, Insights, Regulatory), to deliver sustainable growth in a highly competitive and rapidly evolving environment.

Job Responsibilities:

Lead global Calquence CLL strategy

• Define and drive the global Calquence commercial strategy in CLL, across lines of therapy and treatment segments (FD, TTP, R/R)

• Shape the treatment paradigm evolution, including the shift toward finite-duration regimens

• Ensure clear competitive positioning vs emerging and established players

Drive lifecycle and launch excellence

• Lead the global brand strategy and execution for key CLL programs (e.g. AMPLIFY and lifecycle initiatives)

• Ensure best-in-class launch readiness and execution across priority markets

• Maximize value across pre-launch, launch and in-line phases

Define and deliver customer engagement strategy

• Develop HCP engagement strategies tailored to CLL segments and customer needs

• Drive impactful scientific exchange, peer-to-peer and omnichannel initiatives

• Ensure a strong and differentiated value proposition across stakeholders

Partner across functions and markets

• Collaborate closely with Global Medical Affairs, Market Access, Insights and regions

• Ensure alignment and consistency of execution across markets

• Act as a key interface between global strategy and local implementation

Drive performance and business impact

• Monitor and assess brand performance, forecasts and competitive dynamics

• Identify risks and opportunities to maximize growth and mitigate erosion

• Contribute to business cases, LTP and investment prioritization

Education, Qualifications, Skills and Experience

• 10 years of progressive experience in pharma commercial roles, ideally in CLL or haematology.

• Proven track record in global brand strategy and launch execution

• Strong experience in pre-launch and in-line brand management

• Demonstrated ability to lead in a matrix environment and influence without authority

• Strong strategic thinking and business acumen (forecasting, insights, competition)

• Experience working with cross-functional teams (Medical, Access, Insights, etc.)

• Excellent communication and stakeholder management skills

• 10+ years’ experience in pharmaceutical development and commercialization

• Bachelor's Degree in relevant field

The annual base pay for this position ranges from 231,989 to 347,983.  Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

30-Mar-2026

Closing Date

29-Apr-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.