Director, Site Operations Procurement (Frederick Manufacturing Center Lead)

Role Overview 

Director, Site Operations Procurement is the senior procurement leader for the Frederick Manufacturing Center (FMC), a large-scale Bulk Drug Substance (BDS) site with multiple manufacturing trains and significant expansion plans over the next five years The role owns end-to-end site spend and value delivery, partners closely with site leadership to enable reliable operations and growth, and leads the local procurement team to implement global category strategies while owning local supplier sourcing and supplier relationship management (SRM). Serve as a strong influencer amongst executives, opinion drivers, and key stakeholders. Combine superior negotiation skills, business acumen, communication, and group facilitation skills with the ability to promote an all-inclusive high-performing culture to ensure business needs are met or surpassed. 

Purpose 

• Enable site performance and growth: Provide strategic and operational procurement leadership to support reliable BDS manufacturing across multiple trains and deliver on the expansion roadmap 

• Own site spend and value: Be accountable for total site spend (direct, indirect, and capital where in scope), driving supply delivery, savings, risk mitigation, and supplier-enabled innovation including alignment to Finance on recognized savings and forecast accuracy, working capital improvement, and TCO-based decision making. 

• Align global, deliver local: Support the implementation of global category strategies; lead local sourcing and SRM for site-specific suppliers and contracts. 

Key Responsibilities 

• Americas Procurement leadership & cross-site value: Member of the Americas Procurement Leadership Team; collaborate with US site leads to harmonize strategies and deliver cross-site value, leveraging scale to accelerate Source to Contract and sustainability in line with AZ’s procurement 2, 2, 2 strategy ($2BN in effective savings; 2x the speed of source to contract; 2mtCO2 scope 3 reduction pathway confirmed with suppliers). 

• Operations partnering & stakeholder engagement: Embed with the Site Heads, leadership team, and core functions (Manufacturing, MSAT, Quality, Engineering/Projects, Supply Chain/Planning, EH&S, Facilities, Finance, Legal); drive early procurement engagement in planning and capital approvals, translate operational needs into sourcing plans, and communicate priorities, risks, and outcomes to enable fast, compliant decisions. 

• Strategy & spend ownership: Establish the site procurement strategy with integrated financial targets (productivity, inflation management), supply chain resilience objectives (dual sourcing, OTIF), and Facilities/Engineering reliability outcomes (asset uptime, cost per asset). 

• Global category collaboration and localization: Partner with Global Category Leads to understand strategy and co‑translate it into site‑specific execution plans that meet site needs while delivering category goals; align on preferred suppliers, standards, contracts, and wave plans, and provide clear site demand signals, constraints, and readiness inputs to shape category designs. 

• Local sourcing & SRM: Lead sourcing and SRM for local suppliers, including performance reviews, risk mitigation, lifecycle management, and continuous improvement initiatives. 

• Capital projects & Engineering collaboration: Establish and operate a size‑based CAPEX RACI with the Global Engineering Category Team—Global leads major capital initiatives and site Procurement leads smaller projects—ensuring alignment to global standards, preferred suppliers, and local compliance. 

• Compliance & governance: Ensure adherence to AZ Code of Ethics, SHE standards, Financial Control Framework, Sarbanes‑Oxley, and applicable US regulations (cGMP, OSHA/EPA, labor). 

• Risk & assurance: Lead site procurement risk management, including supply assurance, business continuity, dual sourcing where feasible, and proactive lifecycle management of critical suppliers and materials. 

• Performance management: Set and report KPIs (eg. savings, compliance, ontime delivery, supplier quality, cycle time, risk indicators); maintain value tracking in the procurement value database and support annual budgeting (MTP). 

• Contracting & negotiation: Oversee development, negotiation, and management of site-specific contracts; support execution of global framework agreements at site, ensuring local onboarding and adherence. 

• Team leadership: Line-manage the site procurement team; provide clear direction, coaching, mentoring, succession planning, and capability development; develop a strong performance and engagement culture, while maintaining Great Place to Work. 

• External suppliers & market insight: Engage local strategic suppliers and monitor local supply markets to inform sourcing strategies and drive performance, resilience, sustainability, and innovation. 

• Continuous improvement: Identify and lead improvement initiatives and project teams in support of site’s longer-term strategy; develop and maintain service level agreements with key internal customers. 

• Regional / Global Governance: Ability to act as a regional or global champion to drive performance for key objectives across multiple regions.   

Typical Accountabilities  

• Policy alignment: Conduct activities consistent with AZ Values, Code of Ethics, and supporting Policies and Standards; complete mandatory training on time; proactively report potential noncompliance. 

• Resource planning: Plan, manage, and optimize team resources to meet site needs across direct, indirect, and capital categories, while playing to their strengths and developing their gaps. 

• Change introduction: Oversee introduction of new processes and services from business need identification through formal acceptance by stakeholders. 

• Knowledge sharing: Disseminate best practices; coach the team; contribute lessons learned and benchmarking insights to global procurement networks. 

Education, Qualifications, Experience, and Capabilities 

Essential 

• 10–15 years of progressive procurement experience, including 5+ years leading teams and significant experience with expansion/CAPEX programs; experience in biopharma industry 

• Bachelor’s degree or equivalent; advanced degree a plus. 

• Strategic sourcing and SRM track record across direct, indirect, and capital categories; strong commercial acumen. 

• Contract Negotiation ability to effectively negotiate highly complex contracting scenarios in a fast-paced environment 

• Project and change management skills, including support for major site expansions and CAPEX programs. 

• Risk management expertise (IRM, supply assurance, compliance controls). 

• Stakeholder influence: Ability to partner with senior site leaders and drive cross-functional outcomes. 

• Proven partnership with Finance on value recognition, TCO modeling, and budget governance; experience integrating procurement with Supply Chain planning (MPS/MRP) and with Facilities/Engineering for CAPEX/EPCM delivery and asset reliability. 

• Pharma experience within a manufacturing site

Desirable 

•  Systems proficiency: SAP and Coupa; strong analytical and financial skills. 

• Experience in Bulk Drug Substance (or other Bio/Aseptic Process) manufacturing context and multitrain operations. 

• Proven lean leadership and continuous improvement in procurement. 

• Professional procurement qualifications (e.g., CPSM, CIPS) and experience with complex CAPEX/EPC/EPCM procurement. 

• Experience with should‑cost modeling, indexation/hedging, construction claims management, energy procurement, and reliability-centered maintenance (RCM) 

• Multisite or global network procurement experience.site or global network procurement experience. 

• Regulatory understanding: Working knowledge of cGMP and US safety/environmental regulations; adherence to AZ Code of Ethics and Financial Control Framework (FCF).

The annual base pay for this position ranges from 145,638.40 - 218,457.60 USD Annual (80% - 120%). Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge
perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual 
flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:
Here, your leadership will directly power the consistent delivery of medicines by bringing diverse disciplines together to solve practical problems at speed. You will operate with an enterprise lens, influence decisions across functions and partners, and use cutting-edge tools to turn insights into action. We champion bold ideas and thoughtful execution, valuing kindness alongside ambition, and we invest in transforming how we source and collaborate so you can grow your impact while helping patients receive the treatments they need.

Call to Action:
Step into this site leadership role to secure supply and shape how medicines reach patients—take the lead at Frederick and make your impact felt.

Date Posted

19-Feb-2026

Closing Date

12-Mar-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.