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Director, People Business Partner

Bridgebio

San Francisco - 1800 Owens Hybrid permanent

Posted: February 24, 2026

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Quick Summary

We are seeking a highly experienced Director of People Business Partner to lead our biotech team and drive innovation in rare disease research and development.

Job Description

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on   In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.    Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.

What You'll Do

We are looking for someone that thrives in a rapidly changing, ambiguous environment. Embraces change, is continuously learning, and approaches each day with an improvement-focused mindset. You are a culture champion, talent identifier, performance overseer, and services beacon where execution is always the goal. You will play a critical role in aligning People strategies with business objectives to drive organizational performance. Acting as a trusted advisor, the People Partner collaborates with senior leaders and key stakeholders to provide strategic HR guidance and support across multiple business functions. This position requires deep expertise in HR practices, excellent interpersonal skills, and the ability to influence business decisions to drive sustainable growth and a high-performing culture. The ideal candidate will have experience working for a public company in the life sciences or tech sector.

Responsibilities


Partner with business leaders to understand organizational goals, challenges, and opportunities; advise on People strategies that support business success.


Serve as a trusted advisor and coach to senior leaders, providing insights on employee engagement, retention, performance management, and organizational development.


Lead People programs within client group talent management initiatives, including performance management, workforce planning, succession planning, leadership development.


Leverage AI and advanced analytics to enhance workforce planning, talent insights, organizational design, and decision-making at scale.


Partner with COE’s with administering people related programs, compensation, community, benefits and leave of absence, workforce analytics


Address complex employee relations issues and ensure compliance with company policies, labor laws, and regulations. Provide guidance to managers on conflict resolution, disciplinary actions and performance improvement plans.


Collaborate with Talent Acquisition teams to develop and execute effective recruitment strategies, ensuring the attraction of top-tier talent.


Lead initiatives to enhance organizational design, optimize team structures, and ensure efficient business operations.


Support change management efforts during organizational transitions, acquisitions, or other business transformations.


Partner with legal, ensuring adherence to employment laws and company policies.


Foster strong relationships across business units, ensuring that People priorities are understood and supported by leadership.

Where You'll Work

This is a hybrid role and requires in-office collaboration 2-3x per week in our San Francisco Office.

Who You Are


Minimum of 10 + years of progressive HR experience with at least 10 years in a strategic HRBP role


Bachelor’s degree required or equivalent experience


Experience working in a Life Sciences organization who have a commercialized product a plus


Strong knowledge of HR best practices, employment law, and organizational development principles.


Demonstrated experience applying AI-enabled tools or insights to improve People processes, strategic planning, or leader decision-making.


Excellent communication, interpersonal, and conflict resolution skills.


Ability to build strong relationships at all levels of the organization, from executives to individual contributors.


High level of business acumen and ability to align HR initiatives with business objectives.


Strong data analysis skills with the ability to leverage metrics to drive decision-making.


10 % travel

• You have demonstrated curiosity and adaptability in adopting AI-powered tools and technologies

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. 

Financial & Rewards

• Market-leading compensation

• 401(k) with employer match

• Employee Stock Purchase Program (ESPP)

• Pre-tax commuter benefits (transit and parking)

• Referral bonus for hired candidates

• Subsidized lunch and parking on in-office days

Health & Well-Being

• 100% employer-paid medical, dental, and vision premiums for you and your dependents

• Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)

• Fertility & family-forming benefits

• Expanded mental health support (therapy and coaching resources)

• Hybrid work model with flexibility

• Flexible, “take-what-you-need” paid time off and company-paid holidays

• Comprehensive paid medical and parental leave to care for yourself and your family

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching

• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary
$215,800—$269,800 USD

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