Director, Commercial Project Management

This Director-level role will serve as a key strategic leader, overseeing all aspects of project management, coordination, and implementation for critical commercial programs, including antibody discovery, antibody optimization, antibody expression and purification, site saturation variant libraries, combinatorial variant libraries, and other related SynBio/Biopharma businesses. This role manages all high-level communications to ensure project initiation and completion drive customer satisfaction and directly support commercial objectives and revenue generation. It interfaces strategically with customers, internal scientific and business leadership, finance, and legal regarding agreements, proposals, pricing, statements of work, shipments, and invoicing.

What you will be doing

• Lead and develop two Project Management Managers, setting clear priorities, performance expectations, and grow capabilities aligned to commercial objectives.

• Provide strategic oversight of the project management function, ensuring consistent execution in support of Sales and revenue goals.

• Act as the senior escalation point for high-value, complex customer projects, ensuring a high-touch, commercially focused response.

• Oversee critical project phases including feasibility, scoping, resourcing, execution, risk management, and delivery to commercial success.

• Align project priorities, capacity, timelines, and budgets with quarterly and annual Sales targets.

• Partner with operations leadership and scientific teams to resolve complex issues and implement scalable, commercially viable workflows.

• Deliver concise, executive-level project and forecast updates to Sales Leadership, Finance, and other key stakeholders.

• Maintain a high-level view of project pipeline and WIP, reporting status, risks, and commercial impact in weekly leadership reviews.

• Define and track key project and commercial metrics, including revenue conversion, on-time delivery, and capacity utilization.

• Support Sales enablement through strategic input on proposals, SOWs, service offerings, and selective customer engagements.

What You’ll Bring to the Team

• 8+ years of progressive project management experience in life sciences or a related field, with 4+ years in a high-impact, customer-facing or commercial leadership role.

• Bachelor’s degree in Biology, Chemistry, or a related field required; advanced degree (e.g., MS, MBA, PhD) and/or significant hands-on laboratory experience are a significant plus.

• Demonstrated strategic ability in managing the entire customer journey, from initial inquiry through service delivery and post-project engagement.

• Strong commercial understanding of service offerings, customer workflows, and their direct impact on revenue.

• Proven ability to influence, lead, and collaborate effectively with cross-functional executive teams, customers, internal operations, and the Sales organization.

• Exceptional track record of successfully managing large-scale, complex projects to exceed customer expectations and meet commercial objectives.

• Exceptional leadership, teamwork, and executive-level communication skills.

• A proactive, high-energy, and positive attitude with a strategic, results-driven mindset.

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.