Director, Clinical Core Lab

About Cleerly

We’re Cleerly – a healthcare company that’s revolutionizing how heart disease is diagnosed, treated, and tracked. We were founded in 2017 by one of the world’s leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and sales leaders. We raised $223M in Series C funding in 2022 which has enabled rapid growth and continued support of our mission. In December 2024 we received an additional $106M in a Series C extension funding. Most of our teams work remotely and have access to our offices in Denver, Colorado, New, York, New York, Dallas, Texas, and Lisbon, Portugal with some roles requiring you to be on-site in a location.

Cleerly has created a new standard of care for heart disease through value-based, AI-driven precision diagnostic solutions with the goal of helping prevent heart attacks. Our technology goes beyond traditional measures of heart disease by enabling comprehensive quantification and characterization of atherosclerosis, or plaque buildup, in each of the heart arteries. Cleerly’s solutions are supported by more than a decade of performing some of the world’s largest clinical trials to identify important findings beyond symptoms that increase a person’s risk of heart attacks.

At Cleerly, we collaborate digitally and use a wide variety of systems. Our people use Google Workspace (GMail, Drive, Docs, Sheets, Slides), Slack, Confluence/Jira, and Zoom Video, prior experience in these areas is a plus. Role or department specific technology needs may vary and will be listed as requirements in the job description.

While we are mostly a remote company, travel is required for some team meetings and cross function projects typically once per month or once per quarter, for some roles like sales or external facing roles travel could be up to 90% of the time.

About the Opportunity

Cleerly's services are rapidly scaling up, and we are seeking a highly organized leader with deep experience in cardiac imaging research, core lab operations, and clinical education to serve as the Director, Clinical Core Lab. In this multifaceted role, you will be the primary organizer, educator, and overreader for the US Core Lab. You will provide expert oversight, direct contract physician overreaders, and ensure the operational and quality compliance of our CCTA analysis processes. This position is ideal for an experienced researcher passionate about applying clinical rigor, organizational structure, and educational programs to scale impact in a fast-paced, technology-driven environment.

TTC*: $245,295 - $342,815

*Total Target Compensation (TTC): Total Cash Compensation (including base pay, variable pay, commission, bonuses, etc.). We hire employees anywhere within the United States and account for geography when determining base salary.

Each role at Cleerly has a defined salary range based on market data and company stage. We typically hire at the lower to mid-point of the range, with the top end reserved for internal growth and exceptional performance. Actual pay depends on factors like experience, technical depth, geographic location, and alignment with internal peers.

Responsibilities

Core Lab Organization, Quality & Administration

•

• Case Escalation & Overreading: Serve as a first-line clinical resource for
technologists and the primary escalation reviewer (overreader), providing expert
interpretation and assisting with complex case triage.

• US Core Lab Oversight: Oversee the organization, workflow, and resource
management of the entire U.S. Core Lab operation, ensuring efficiency, accuracy,
and standardization in CCTA plaque analysis.

• Overreader Direction & Scheduling: Direct, schedule, and manage our team of
contract physician scan reviewers (overreaders), ensuring adequate coverage
and timely review capacity.

• Quality Control (QC) & Regulatory Alignment: Oversee the quality control (QC)
process of the U.S. Core Lab, including conducting random audits of CCTA
cases. Work directly with the Regulatory and Quality Affairs teams to ensure that
core lab processes and documentation meet all regulatory submission
requirements.

• Administration & Tactical Support: Provide essential administrative and tactical
support to the Core Lab operation, serving as the hands-on organizer while
driving education and standardization.

Clinical Education & Training (in partnership with the VP of Clinical Affairs)

•

• Training Program Leadership: Co-develop and deliver scalable educational
programming targeting core lab staff, new physician readers, and broader clinical
audiences.

• New Reader Onboarding & Mentorship: Lead the clinical training and onboarding
of new contract physician readers, ensuring they achieve consistency and
accuracy in plaque analysis.

• Clinical Support Program: Support the VP of Clinical Affairs in designing and
executing Cleerly’s Clinical Support Program for strategic accounts, helping
deliver timely software training, case-based learning, and updates on the latest
developments in coronary plaque imaging.

Research & Cross-Functional Collaboration

•

• Core Lab Interface: Act as the organizational liaison between the US Core Lab
and Cleerly’s Medical and Scientific Affairs teams to support select external
research efforts.

• Core Lab Protocol Development: Leverage research expertise to refine and
standardize internal analysis protocols within the core lab to maintain
consistency and rigor.

• Manuscript/Abstract Support: Assist with manuscript and abstract review to
ensure clinical and scientific accuracy and alignment with Cleerly’s products and
published literature.

Requirements

•

• PhD or MD with advanced training in Cardiology or Radiology, and a minimum of
3 years interpreting CCTA studies, either as part of clinical fellowship/faculty
appointment, or a research/core lab experience.

• We are open to candidates who are FMG (Foreign Medical Graduates) without a
current US license.

• Expert in CCTA imaging analysis, with significant experience leading or operating
a Core Lab in an academic or industry setting.

• Proven background in clinical research and trial management, with a strong
understanding of data handling, protocol development, and regulatory
documentation requirements.

• Experienced educator and trainer with a track record of teaching or clinical
training in cardiovascular imaging.

• Highly organized and versatile leader who can operate effectively at both the
administrative/tactical level and the strategic level.

• Clinically sharp, organized, and confident providing constructive feedback to
peers and technologists.

• Comfortable speaking with clinicians, researchers, and internal stakeholders,
from product to sales.

Working at Cleerly takes HEART. Discover our Core Values:

• H: Humility- be a servant leader

• E: Excellence- deliver world-changing results

• A: Accountability- do what you say; expect the same from others

• R: Remarkable- inspire & innovate with impact

• T: Teamwork- together we win

Don’t meet 100 percent of the qualifications? Apply anyway and help us diversify our candidate pool and workforce. We value experience, whether gained formally or informally on the job or through other experiences. Job duties, activities and responsibilities are subject to change by our company.

OUR COMPANY IS AN EQUAL OPPORTUNITY EMPLOYER. We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation.

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