Cell & Gene Therapy Technician
IntegratedResourcesINC
Posted: April 9, 2015
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Quick Summary
Help with operational start-up of a new CART process development lab space. Assist with setting up the lab and ensuring the smooth operation of the new process. This is a critical role that requires attention to detail and a strong understanding of laboratory procedures.
Required Skills
Job Description
A Few Words About Us
Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.
• Help with operational start-up of a new CART process development lab space
• Participate in information/ tech transfer from external collaborator and implementation of CART processing technologies (T-cell isolation, activation, genome-engineering, expansion, cryopreservation, and supporting/ associated analytical characterization methods)
• Contribute to relevant and impactful innovation programs to enhance CART manufacturing technologies/ capabilities and work-processes (such as alternate transfection/ cell engineering strategies, media development, disposable/ closed production systems and automation) as needed/ appropriate.
• Work closely with Project Team and key partners - communicate and collaborate effectively to ensure seamless interfaces and interactions with all stakeholder groups
• Apply scientific and technical experience to establish safe, high-quality lab practices, and demonstrate strong personal leadership and technical and interpersonal skills
• Ensure high-quality, timely documentation in electronic laboratory notebooks and contribute to and Technical Reports as appropriate.
• PhD degree in Molecular Immunology/ Molecular Biology or related field or Chem. Engineering degree (with appropriate bioprocessing, cell and gene therapy focus) with 4+ years of postgraduate experience (or MSc with 7+ years) in biotech/ bio-pharma industry (preferably in the development and characterization of manufacturing processes for cell- or gene-based therapies).
• Process development for GMP bio-manufacturing (DOE, media development, disposable processing technologies, automation - prior experience with cell- or gene-therapy process development preferred)
• Relevant cell and molecular biology experience such as production/ characterization of recombinant viruses or growth and molecular engineering of primary T cells.
• Familiarity with cGMP and relevant Regulatory Guidance documents.
• 1-3 years of experience in Cell/Tissue Culture.