Biostatistician in Statistical Methodology – Director

Job Title: Biostatistician in Statistical Methodology – Director

Location: Cambridge

Salary:  Competitive

At AstraZeneca, we are committed to pushing the boundaries of science to transform the lives of patients living with cancer. Our Oncology Biometrics department plays a crucial role in this mission by driving excellent design and generating the data needed for informed decision-making. As part of our Statistical Innovation group within the Oncology Biometrics department, you will have the opportunity to develop creative statistical ideas and apply them in your work. You will join a team of experts dedicated to finding solutions at critical stages in the drug development cycle, working in a dynamic and ever-evolving environment.

Accountabilities:

• Lead capability building in statistical areas such as clinical trial design and analysis, exploratory and secondary analysis of clinical trial and observational data.

• Provide expert consultancy on key issues for statisticians, medical scientists, and other roles across the business.

• Collaborate internally and externally, leading strategic activities that impact clinical trial design and analysis.

• Develop and implement new methodologies, engaging with external scientists and regulators through publications and collaborations.

• Identify new areas where Statistical Innovation can add value and build relationships with the external scientific community.

Essential Skills/Experience

• Education to a MSc or PhD in Statistics, Biostatistics or Mathematics or a related discipline, followed by experience of independent academic research and/or clinical drug development.

• Strong track record and ability of delivering innovative statistical solutions in an applied environment related to at least one of the following areas: analysis of clinical trial and observational data, survival modelling and analysis, Bayesian analysis, cancer epidemiology.

• Strong knowledge of programming in R and/or SAS

• High level of competence in global and cross-skilled collaborative working

• Track record of research and methodological development in Statistics, supported by scientific publications in first class statistical journals

• Desire to apply your scientific competence on practical problems for the benefit of patients

Desirable Skills/Experience:

• Knowledge/research experience in the development of statistical methodology related to the analysis of large-scale health database, dose finding and escalation in clinical trials, meta-analysis, Bayesian statistics, longitudinal modelling.

• Broad awareness of statistical issues against the evolving scientific and regulatory landscape. Experience with oncology drug development.

• Documented ability to deliver innovative statistical solutions should be in at least 2 of the areas listed above or be a recognised expert in one of these areas and an extensive publication record is expected.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, you will be part of a pioneering team that is transforming cancer treatment. With one of the broadest Oncology pipelines in the industry, you will have the chance to work on next-generation drug modalities and embrace our expanding toolkit. Our collaborative environment fosters courage and curiosity, empowering you to take smart risks and challenge norms. By joining us, you will contribute to meaningful advancements in patient care while growing alongside top experts from around the world.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

We welcome your application not later than 12th April 2026

Ready to make a difference? Apply now to join our team and help shape the future of cancer treatment!

Date Posted

27-Mar-2026

Closing Date

12-Apr-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.