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Bioinformatics Scientist

Axle

Rockville, MD (Axle Informatics LLC) permanent

Posted: December 19, 2025

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Job Description

(ID: 2025-1346)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

• 100% Medical, Dental & Vision Coverage for Employees

• Paid Time Off (Including Holidays)

• Employee Referral Bonus

• 401K Match

• Tuition reimbursement and professional development opportunities

• Flexible Spending Accounts:

• Healthcare (FSA)

• Parking Reimbursement Account (PRK)

• Dependent Care Assistant Program (DCAP)

• Transportation Reimbursement Account (TRN)

Overview

Axle is looking to add a driven, flexible, organized, and meticulous Bioinformatics Scientist to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Structural Bioinformatics Core (SBIS), Vaccine Research Center (VRC).

Technical Requirements:

• Utilize computer simulation expertise such as molecular dynamic and monte carlo simulations to solve protein structures’ dynamics and mechanism of protein-protein interaction.

• Develop and apply in silico tools to design vaccine and therapeutic products against diverse pathogens, including HIV-1, Influenza, or Malaria.

• Develop methods to study vaccin-elicited immune responses, including antibodies’ sequence and structural analysis.

• Develop and apply custom-made AI/ML tools to analyze vaccine outcomes.

• Serve as expert to identify critical/biological findings of experimental data and collaborate with other scientists.

• Utilize High performance computing (HPC) to bring the state-of-the-art techniques such as machine learning, artificial intelligence, deep learning to vaccine target protein design.

• Co-lead on projects, including (but not limited to) HIV-1 Malaria, Influenza and Lassa) and coordinate with scientists from other organizations or institutions involved in similar or related research projects.

• Provide scientific expertise to facilitate protein and vaccine design.

• Mentor interns and postbaccalaureate scientists.

• Publish the findings and analysis in peer-reviewed journals.

Specific Qualifications:

• PhD in Computational Biology/Chemistry or a related field is required.

• 2-3 years of postdoctoral experience is required.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [email protected]

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$110,000—$125,000 USD

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