Bioinformatician II

About OICR

OICR is Ontario’s cancer research institute. We bring together people from across the province and around the world to improve the lives of everyone affected by cancer. We take on the biggest challenges in cancer research and deliver real-world solutions to find cancer earlier and treat it more effectively. We are committed to helping people living with cancer, as well as future generations, live longer and healthier lives.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges, Universities, Research Excellence and Security.

Job Details

Position: Bioinformatician II

Location: MaRS Centre, Toronto

Department: Computational Biology (Pai Lab)

Reports To: Principal Investigator I

Hiring Range: $66,000 - $74,100 per annum commensurate with level of experience; total compensation includes a competitive benefits plan, plus a defined benefit pension plan (HOOPP) 

Hours: 35 hours/week

Job Type: Hybrid

Status: Full-time, Temporary (1-year contract)

Position Summary

The Ontario Institute for Cancer Research (OICR) is looking to fill an existing vacancy for a Bioinformatician II to join the Computational Biology team.

The Bioinformatician II will support research projects involving genomic analysis, particularly of single-cell genomics data. The successful candidate will work closely with computational biologists and wet-lab scientists to process, analyze, and interpret single-cell and bulk tissue ‘omic data. The immediate team need is for single-cell RNAseq and ATACseq analysis for an exciting ongoing project with prospect of manuscript submission within the year. This role is ideal for candidates interested in applying computational methods to biological questions in a collaborative research environment.

This position is temporary, full-time for one-year.

Position Responsibilities

Perform preprocessing and quality control of single-cell and bulk sequencing datasets.

Conduct downstream analyses such as dimensionality reduction, clustering, differential expression/methylation analysis, and cell type annotation, among others.

Integrate multi-sample and multi-modal datasets (e.g., scRNA-seq, ATAC-seq) using Seurat or related tools.

Generate publication-quality visualizations (e.g., UMAP/t-SNE plots, heatmaps, violin plots).

Assist in the interpretation of results and contribute to biological insights.

Collaborate with experimental researchers to design analyses and validate findings.

Maintain reproducible workflows and well-documented code (e.g., R scripts, R Markdown, Git).

Support preparation of figures, reports, and manuscripts.

Position Requirements

Master’s degree in Bioinformatics, Computational Biology, Genomics or a related field, or recognized equivalent.

Working experience with single-cell analysis workflows in Seurat. Experience must be through real-world projects.

Experience with Linux/Unix environments and high-performance computing (HPC).

Understanding of next-generation sequencing (NGS) data and single-cell genomics concepts.

Basic knowledge of statistics and data analysis techniques.

Strong organizational and communication skills.

Analytical thinking and problem-solving skills.

Attention to detail and data integrity.

Ability to work both independently and in a team setting.

Strong time management skills, with the ability to prioritize tasks, work effectively within a supervisory structure, and meet project deadlines.

For more information about OICR, please visit the website at www.oicr.on.ca.

To learn more about working at OICR, visit our career page.

POSTED DATE:         April 14, 2026
CLOSING DATE:       April 17, 2026 at 2:00 p.m. 

OICR is committed to fostering a climate of equity, diversity, inclusion, and accessibility. This commitment is central to, and mutually supportive of, our research excellence mandate. We welcome and respect the diversity of all members of our community and we support an inclusive culture for all. We welcome all applicants, and encourage applications from racialized persons, Indigenous Peoples, women, persons with disabilities, LGBTQ2S persons, and others who may contribute to furthering a diversity of ideas within our community. OICR is committed to fair assessment of a candidate’s abilities, and consideration for diversity of thought, method, and experience. Providing an accessible workplace and recruitment process is important to us, as described in our Accessibility Plan (https://oicr.on.ca/accessibility/).  Should you require accommodation during any stage in the recruitment process, please complete the form at the bottom of page https://oicr.on.ca/careers/. Information received related to accommodation will be handled confidentially.  

OICR hiring managers may use approved Artificial Intelligence (AI) tools to assist with an initial screening or assessment of applications, and selection of applicants in accordance with OICR’s privacy policies.  Personal information associated with any job application will not be shared with or retained by any third party for the purpose of training an AI model.  Hiring managers shall determine which applications proceed through the recruitment process.

Resume Format: If you elect to apply, please click on the “Apply for this Job” button below.  You will be required to enter contact details, and to attach your resume to your application. Please attach your resume as a .pdf or .doc file.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.