Associate Director/Senior Manager, LNP PD, Cell Therapy

Key Responsibilities LNP Formulation and Process Development: Develop nucleic acid LNP (Lipid Nanoparticle) formulations and manufacturing processes, including component ratio optimization and process development for PD/AD/QC stages. Formulation Evaluation and Optimization: Evaluate, adjust, and optimize LNP formulations and processes. Develop analytical methodologies and quality standards for raw materials, intermediates, final products, and manufacturing steps. CDMO and Supplier Management: Participate in the management and supervision of CDMOs and raw material suppliers to ensure project quality, progress, and compliance. Regulatory Documentation Support: Assist project leaders in data compilation and documentation preparation for IND submissions and regulatory filings. Other Tasks: Complete other duties as assigned by leadership. Qualifications Education: Ph.D. in Nanobiomaterials, Organic Chemistry, Bioengineering, or related scientific disciplines. Technical Expertise: Hands-on experience in nanoparticle or liposome technology, including process development, analytical method development/optimization, and quality specification establishment. Process Knowledge: Deep understanding of LNP formulation processes and related unit operations such as nanoparticle encapsulation and ultrafiltration/diafiltration. Familiar with analytical and quality control techniques, CMC development principles, and GMP/industry quality standards. Communication Skills: Strong ability to read and interpret English scientific literature. Capable of technical writing for process and analytical method development. Excellent oral communication and cross-functional collaboration skills. Preferred: Proven track record in successful development and regulatory submission (including IND filing or clinical approval) of nanoparticle-based drug delivery systems. Date Posted 05-1月-2026 Closing Date AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.