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Associate Director/Director, Government Pricing

Axsometherapeutics

New York, NY (NYC Headquarters) Remote permanent

Posted: November 24, 2025

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Quick Summary

We are seeking an Associate Director/Director to lead our CNS treatment efforts, leveraging expertise in neuroscience and a strong track record of success in developing novel treatments.

Job Description

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Associate Director/Director, Government Pricing to oversee all aspects of Government Pricing, State Price Transparency Reporting and Medicaid Operations. The Associate Director/Director, Government Pricing will be responsible for ensuring compliance with federal and state price reporting regulations, reviewing pricing strategies, ensuring the accuracy and timeliness of Medicaid rebate payments, and collaborating with internal teams to support business objectives. This position reports to the Executive Director, Pricing and Contract Strategy.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.

Job Responsibilities and Duties include, but are not limited to, the following:

• Government Pricing Management

• Ensure accurate and timely submission of pricing data in compliance with federal and state price transparency regulations

• Regulatory Compliance

• Maintain up-to-date knowledge of government pricing and state price transparency regulations and policies

• Ensure adherence to all legal and regulatory requirements

• Medicaid Rebates

• Ensure appropriate and timely payment of Medicaid rebates

• Ensure appropriate execution and payment of approved and finalized Medicaid supplemental and SPAP contracts

• Data Analysis and Reporting

• Analyze pricing data, trends, and prepare and review government pricing reports

• Cross-Functional Collaboration

• Work closely with finance, legal, and market access teams to support pricing strategies and address issues

• Provide guidance on pricing matters and regulatory requirements

• Process Improvement

• Identify and implement process improvements to enhance efficiency and accuracy in pricing and reporting

• Develop and maintain documentation for pricing procedures and controls

• Third Party Processor Management

• Manage ongoing TPP relationships, resolve specific issues, and review and approve TPP billings

• Price Calculation and Reporting

• Calculate and file appropriate prices for federal drug programs (BP, AMP, PHS/340B, NFAMP, FCP/FSS, IFF, URA)

• Knowledge of and ability to handle complex pricing concepts such as discount reallocation, pro-ration, and smoothing

• Team Liaison

• Provide business guidance across teams related to the life sciences commercial and regulatory landscape

• Compliance Oversight

• Ensure adherence to compliance requirements and conduct risk mitigation activities. Manage internal and external audits/reviews and Sox compliance supervision

• Monitoring Regulations

• Actively monitor government pricing regulations related to payer, IDN, policy, competitor, and market conditions to inform critical decisions and potential impacts to reimbursement and federal pricing

• Contract Assistance

• Assist with contract reviews, assessing contractual terms, performing Bona Fide Service Fee tests, Class of Trade Assessment, and other government pricing analysis

• Analytics and Reporting

• Create analytics, graphs, and slides showing policy impacts on government pricing data

• Present findings to Executive Leadership

• FSS Contract Compliance

• Ensure contractual obligations under the Federal Supply Schedule (FSS) contract are met through continuous monitoring of obligations with Federal Acquisition Regulations (FARs) and the Veterans Health Care Act

• Gross to Net Forecasting

• Provide excellent insights to Gross to Net forecasting accuracy and business decisions

• Policy and Procedure Development

• Establish and maintain policies, procedures, and standards in support of Sarbanes-Oxley (SOX) requirements, internal/external financial reporting processes, and government regulations

• Stay abreast of government and state rules and guidance changes

• Stakeholder Collaboration

• Collaborate across all internal and external stakeholders (Market Access Strategy, Contract Operations, GtN, Accounting/Finance, US Public Affairs, Legal, Audit, Commercial leaders, and external Legal and consultants)

Requirements / Qualifications

• Bachelor’s degree in Business, Finance, Accounting, Public Policy, or related field. MBA or other related graduate-level degree is a plus

• Minimum of 7 years of experience in the pharmaceutical/biotechnology industry or state agency, with experience in Government Pricing, Medicaid, and State Price Transparency Reporting, finance, or related government payer/program administration

• Proven track record in managing pricing compliance and reporting and Medicaid rebate payments

• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Strong understanding of government pricing regulations and compliance requirements

• Proficiency in data analysis and financial modeling

• Excellent communication and interpersonal skills

• Ability to work independently and manage multiple priorities

• Detail-oriented with strong analytical and problem-solving abilities

• Experience with Microsoft Office products and advanced Excel techniques

• Ability to manage multiple and competing tasks across functional areas

• High accuracy rate and attention to detail

• Experience with effective management of large datasets and data query tools

• Skilled at financial modeling and pricing policy research (qualitative and quantitative)

• Execute with high personal accountability to meet statutory reporting timelines

• Ability to prioritize and focus on activities that drive value and increase operational effectiveness

• Strong verbal and written communication skills, time management, and organization

• Apply experience, structured thinking, emerging knowledge, and trends to solve problems logically

Salary and Benefits:

The anticipated salary range for this role is $160,000 - $200,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

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