AI Lead, Commercial, Launch & Medical Excellence

Alexion is seeking a visionary AI lead to define and drive the AI strategy across our global Commercial, Launch, Market Access, Patient Engagement, and Medical Affairs organizations. In this highly strategic and influential role, you will partner with business, medical, and field teams to transform complex commercial and medical challenges into high‑value AI‑powered solutions that enhance launch success, deepen customer engagement, and ultimately improve outcomes for patients with rare diseases.

You will lead the development and adoption of advanced AI/ML capabilities that optimize how Alexion brings medicines to the world, from precision launch planning and omnichannel orchestration to real‑world evidence generation and medical insights. This role blends technical expertise with strong product thinking, commercial acumen, and exceptional stakeholder leadership.

You will be responsible for:

• AI Strategy & Portfolio: Identify and prioritize business‑aligned AI opportunities and define the multi-year AI strategy and roadmap. Govern the portfolio from proof‑of‑concept through validation to scaled products, with clear stage gates, success metrics, and value tracking.
• Ownership & Delivery: Act as the product owner for AI solutions (e.g.  segmentation/targeting, next‑best‑action, content personalization, omnichannel optimization, forecasting, and advanced RWE analytics.). Set problem statements, adoption thresholds, and benefits realization plans; oversee delivery with internal teams and partners.
• Business Interface & Partnerships: Serve as the primary interface between Commercial teams, data scientists, and external AI partners. Translate business needs into AI solutions. Evaluate buy‑build‑partner options and manage vendors/consortia.
• Workflow Integration & Change: Lead cross‑functional integration of AI into commercial, medical, CRM, and MSL platforms and workflows ensuring solutions support both field and headquarters teams. Drive change management (stakeholder engagement, training/upskilling, super‑user networks, SOP/role updates, communications, feedback loops) to accelerate adoption and scale.
• Data & Platforms: Partner with the Head of Data and tech teams to ensure data quality and secure integration across commercial data sources. Influence platform choices and manage buy‑build‑partner decisions with clear success criteria and vendor governance.
• Governance, Compliance & Responsible AI: Ensure AI solutions meet privacy, promotional and medical compliance, pharmacovigilance, and audit requirements.
• Impact & Communication: Define OKRs/KPIs tied to business outcomes (e.g., launch ROI, scientific engagement quality and reach, next‑best‑action lift, access wins, patient identification, etc. ). Track and communicate progress, impact, and value to commercial, medical, and executive leadership with clear narratives and evidence.
• Talent & Culture: Build and nurture a cross‑functional network of super‑users and AI champions; set standards and best practices. Foster a culture of scientific rigor, product thinking, innovation, and measurable impact; promote agile ways of working across Alexion.

You will need to have:

• Education: BS in Computer Science or a relevant field required (e.g., Information Systems, Data Science, Engineering). MS or MBA preferred, with strong exposure to biopharma commercial/medical functions and meaningful AI familiarity (coursework, certifications, executive programs, or applied initiatives).
• Experience: 10+ years in biopharma/biotech Commercial, Launch, Market Access, or Medical Affairs; 5+ years leading cross‑functional, technology‑enabled portfolios with measurable outcomes. Demonstrated success sponsoring/directing AI initiatives from concept to scaled adoption; not responsible for hands‑on coding or model development.
• Business Domain Expertise: Deep understanding of commercial business workflows, patient journeys, launch excellence, payer/access dynamics, omnichannel and field operations, and Medical Affairs engagement; proven ability to translate needs into AI‑enabled business solutions.
• Product and Portfolio Leadership: Proven ability to define roadmaps, prioritize portfolios, manage budgets, and deliver measurable impact.
• Stakeholder Management: Credible partner to Market Access, Field Leadership, Medical Affairs, and Data/Tech; influences without authority and aligns internal and external partners.
• Workflow Integration & Change: Experience integrating new capabilities into business workflows; adept at change management, adoption, and benefits realization.
• Data & Governance Fluency: Familiarity with key data domains (claims, pharmacy, EHR/RWD, CRM/engagement, formulary/access, market research, medical insights) and principles for quality, access controls, and lineage/traceability; experienced in vendor management.
• Regulatory & Compliance: Working knowledge of privacy laws, audit and documentation standards, and commercial/medical compliance (promotional review, scientific exchange, adverse event capture). Familiarity with responsible AI and model risk management.
• Technical Fluency (non‑coding): Comfortable engaging with AI/ML concepts such as predictive modeling, NLP/LLMs. Able to assess value, risk, and feasibility; understand AI and platform considerations to make informed decisions and ask the right questions without needing to code or build models.
• Communication & Storytelling: Exceptional ability to simplify AI concepts for scientific and business audiences; craft outcome‑focused narratives and adoption cases; report progress, impact, and value to Commercial and executive leadership with clear evidence and trade‑offs.

We would prefer for you to have:

• Rare disease commercial experience, including small‑population targeting and privacy‑preserving analytics.
• Experience acting as business product owner for AI solutions, driving adoption and measurable outcomes.
• Portfolio financial acumen (investment cases, ROI) and partnership governance (buy‑build‑partner, success measures, IP/publications stance).
 

In-Office/Hybrid Statement:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work on average a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Compensation and other factors:

The annual base pay (or hourly rate of compensation) for this position ranges from $203 213,60 - $304 820,40. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

At AstraZeneca's Alexion division for Rare Diseases you will find an environment where work is more than just a job—it's a mission. Our closeness to patients brings us closer to our work and each other. With a rapidly growing portfolio in a nimble biotech atmosphere supported by global resources, tailored development programs are crafted to improve your skills. These programs encourage a deep understanding of our patients' journeys. Here diversity is valued; inclusion is championed; innovation is celebrated; all while making a profound impact on patients' lives. 

Ready to make a difference? Apply now!

Date Posted

12-feb.-2026

Closing Date

05-mars-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.